Fluorescent oligonucleotides and uses thereof
US6838244B1 · kind B1 · utility
2Cited by
6References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 2001 |
| Grant date | Jan 4, 2005 |
| Priority date | — |
| Expiry date | May 18, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6818
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Oligonucleotide molecules labeled with a plurality of fluorophores of one or more types embedded in the backbone of said oligonucleotide, wherein at least one of said fluorophores is not located at either the 3′ or 5′ terminus of said oligonucleotide. The invention further provide methods for using the subject labeled oligonucleotides in detecting biological molecules, sequencing DNA molecules and particularly generating cDNA molecules for characterizing the differential expression of genes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.