Inhibitors of proteasomal activity for stimulating bone growth
US6838436B1 · kind B1 · utility
48Cited by
14References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 23, 2000 |
| Grant date | Jan 4, 2005 |
| Priority date | — |
| Expiry date | Oct 15, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q7/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that inhibit the activity of the proteasome or the productions of proteasomal proteins and promote bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgey, and post-dental implantation, in subject where this is desirable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.