Prevention of adhesions
US6841153B1 · kind B1 · utility
23Cited by
5References
7Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 1, 1999 |
| Grant date | Jan 11, 2005 |
| Priority date | — |
| Expiry date | Oct 1, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/38
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for the prevention of adhesion formation involve the administration of therapeutic formulations to a patient which include antibodies to TIMP-1 or TIMP-1 antisense oligonucleotides. The formulations can also include suitable carriers, such as a hyaluronic acid matrix, for optimal administration. The treatment procedure can be initiated and monitored by a diagnostic procedure which involves the detection of elevated levels of TIMP-1 in a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.