Method for the preservation of biologically-active material
US6841168B1 · kind B1 · utility
30Cited by
8References
48Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 21, 2000 |
| Grant date | Jan 11, 2005 |
| Priority date | — |
| Expiry date | Jun 21, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Biologically-active material can be preserved by a method of desiccation, without lyophilisation, in a matrix of glassy trehalose. The method involves forming a coacervate of the biologically-active material and chitosan and then dehydrating mixture of coacervate and trehalose solution. In a cycle time much shorter than a typical freeze drying process biologically-active material, such as viruses, proteins and nucleic acids, can be preserved to provide a material that can be rehydrated. The invention is especially useful for the production of vaccines from preserved material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.