Process for the preparation of imidazopyridines
US6841679B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2001 |
| Grant date | Jan 11, 2005 |
| Priority date | — |
| Expiry date | Aug 17, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the general formula (1), in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group; X1 and X2 denote, independently of each other, hydrogen, a halogen, a C1-4 alkoxy, C1-6 alkyl, CF3, CH3S CH3SO2 or NO2 group; and R1 and R2 denote independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen, or a salt thereof, and is prepared by a multi-step process, the last step of which comprises reducing a compound of the general formula (6), in which Y, X1, X2, R1 and R2 are as defined above with an appropriate reducing agent, such as Zn, and, if desired, converting the compound of formula (1) thus obtained, into a salt. The products of this process are known to have useful pharmacological properties, e.g. as anxiolytics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.