Highly selective inhibitors of the urokinase plasminogen activator

US6841702B2 · kind B2 · utility

Assignees

• Wilex Biotechnology GmbH · DE
• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Viktor Magdolen · Tauberbischofsheim, DE
• Stefan Sperl · Birkenfeld, DE
• Joerg Stuerzebecher · Erfurt, DE
• Olaf Wilhelm · Birkenfeld, DE
• Nuria Arroyo De Prada · Barcelona, ES
• Luis Moroder · Martinsried, DE
• Robert Huber · Midland, US
• Uwe Jacob · Birkenfeld, DE
• Wolfram Bode · Gauting, DE

Key dates

• Filing date: Mar 15, 2001
• Grant date: Jan 11, 2005
• Expiry date: Mar 15, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/74
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel selective inhibitors of the urokinase plasminogen activator (uPA, EC 3.4.21.31), of the arylguanidine type.