Modular protein libraries and methods of preparation
US6844161B2 · kind B2 · utility
41Cited by
3References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 31, 1998 |
| Grant date | Jan 18, 2005 |
| Priority date | — |
| Expiry date | Aug 31, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel proteins and protein libraries are disclosed. The proteins possess one or more functional protein modules from different parent protein molecules. The proteins and protein libraries are exemplified by the preparation of cross-over chemokines that contain various combinations of peptide segments derived from RANTES, SDS-1 and vMIP-I and to vMIP-II. The proteins and libraries are extremely pure and can be provided in non-limiting high yields suitable for diagnostic and high-throughput screening assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.