Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor
US6844361B2 · kind B2 · utility
1Cited by
5References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 4, 2003 |
| Grant date | Jan 18, 2005 |
| Priority date | — |
| Expiry date | Feb 4, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/403
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to a pharmaceutical composition comprising the sodium-hydrogen exchanger (NHE) inhibitor cariporide and an angiotensin converting enzyme (ACE) inhibitor which exhibits unexpectedly efficacious properties for preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life, and to methods of preventing heart failure and other age-related organ dysfunctions, age-related disorders and for prolonging life comprising administering pharmaceutically effective amounts of the sodium-hydrogen exchange inhibitor cariporide and an ACE inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.