Pharmaceutical Composition

US6844459B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Birgit Hauer · Lahr (Eifel), DE
• Armin Meinzer · Glückstadt, DE
• Ulrich Posanski · Glückstadt, DE
• Jacky Vonderscher · Riedisheim, FR

Key dates

• Filing date: May 20, 2003
• Grant date: Jan 18, 2005
• Expiry date: Dec 25, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C11C3/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical compositions comprising a cyclosporin in a novel galenic formulations for oral administration. The compositions typically comprise a cyclosporin, 1,2-propylene glycol, a mixed mono-, di- and tri-glyceride and a hydrophilic surfactant. Further a refined glycerol-transesterified corn oil is provided representing a mixed mono-, di- and tri-glyceride suitable for the novel formulation. Dosage forms include in particular oral dosage forms.