Patent · US Expired

Oncoprotein protein kinase

US6846644B2 · kind B2 · utility

1Cited by
10References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 18, 2001
Grant dateJan 25, 2005
Priority date
Expiry dateMay 18, 2021

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/91215
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD as determined by reducing SDS-PAGE, having serine and threonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.