Neurokinin antagonists for use as medicaments

US6846814B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Jeffrey S. Albert · Montréal, CA
• Peter Bernstein · Wallingford, US
• Cyrus J. Ohnmacht · Wilmington, US
• Keith Russell · Wilmington, US
• Ashokkumar B. Shenvi · Wilmington, US

Key dates

• Filing date: Apr 5, 2001
• Grant date: Jan 25, 2005
• Expiry date: Jun 13, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds having the general formula wherein R1a, R1b, R1c, R2, R3, R4, R5, R6, R7, R8, X1, X2, Y, Z and n are as defined in the specification, methods of using such compounds for the treatment of diseases and pharmaceutical composition comprising such compounds.