Bicyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them

US6846824B2 · kind B2 · utility

Assignee

• DR. REDDY'S LABORATORIES LIMITED · IN

Inventors

• Braj Bhushan Lohray · Hyderabad, IN
• Vidya Bhushan Lohray · Hyderabad, IN
• Ashok Bajji · Hyderabad, IN
• Shivaramayya Kalchar · Taipei, TW
• Rajagopalan Ramanujam · Hyderabad, IN
• Ranjan Chakrabarti · Hyderabad, IN
• Javed Iqbal · Hyderabad, IN
• Ranga Madhavan Gurram · Hyderabad, IN

Key dates

• Filing date: Mar 23, 2001
• Grant date: Jan 25, 2005
• Expiry date: Feb 7, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D279/16
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I) its tautomeric forms, its stereoisomers, its polymorphs, its pharmaceutically acceptable salts or its pharmaceutically acceptable solvates can be used to prevent or treat diabetes caused by insulin resistance or impaired glucose tolerance or complications of diabetes caused by insulin resistance or impaired glucose tolerance. The compounds can also be used to reduce cholesterol, body weight, blood glucose, triglycerides and free fatty acids in the blood.