LO-CD2a antibody and uses thereof for inhibiting T cell activation and proliferation
US6849258B1 · kind B1 · utility
4Cited by
6References
8Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 18, 1997 |
| Grant date | Feb 1, 2005 |
| Priority date | — |
| Expiry date | Jul 18, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.