Patent · US Expired

Microfabricated devices for the storage and selective exposure of chemicals and devices

US6849463B2 · kind B2 · utility

112Cited by
63References
38Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 19, 2002
Grant dateFeb 1, 2005
Priority date
Expiry dateDec 19, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Microchip devices and methods of use are provided for the controlled exposure of a secondary device. In one embodiment, the microchip device include a substrate, a plurality of reservoirs in the substrate, a secondary device in one or more of the reservoirs, at least one barrier layer covering each of the reservoirs to isolate the secondary device from an environmental component outside the reservoirs, wherein the barrier layer is impermeable to the environmental component, and a microprocessor-controlled actuation means for rendering the barrier layer porous or permeable to the environmental component to expose the secondary device to said environmental component. The secondary device can comprise a sensor or sensing component (e.g., a biosensor). In other embodiments, microchip devices are provided for the controlled exposure of a reacting component, such as an enzyme. In still other embodiments, sensors are provided on the device outside of the reservoirs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.