Piperidine compounds

US6849621B2 · kind B2 · utility

Assignees

• SCHERING CORPORATION · US
• Pharmacopeia Drug Discovery, Inc. · US

Inventors

• Stuart B. Rosenblum · West Orange, US
• Qingbei Zeng · Shanghai, CN
• Mwangi W. Mutahi · Orange, US
• Robert G. Aslanian · Rockaway, US
• Pauline C. Ting · New Providence, US
• Neng-Yang Shih · Lexington, US
• Daniel M. Solomon · Edison, US
• Jianhua Cao · Laishui, CN
• Henry A. Vaccaro · South Plainfield, US
• Kevin D. McCormick · Berkeley Heights, US
• John J. Baldwin · Gwynedd Valley, US
• Ge Li · Shanghai, CN

Key dates

• Filing date: Mar 11, 2002
• Grant date: Feb 1, 2005
• Expiry date: Apr 12, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed are novel compounds of the formula Also disclosed are pharmaceutical compositions comprising the compounds of Formula I.Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I.Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I in combination with a H. receptor antagonist.