Muteins of hypoxia inducible factor alpha and methods of use thereof
US6849718B2 · kind B2 · utility
22Cited by
4References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 19, 2002 |
| Grant date | Feb 1, 2005 |
| Priority date | — |
| Expiry date | Mar 19, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides hypoxia inducible factor alpha muteins, DNA sequences encoding these hypoxia inducible factor alpha muteins, recombinant DNA molecules containing those DNA sequences operatively linked to expression control sequences and capable of inducing expression of an hypoxia inducible factor alpha muteins, hosts transformed with those recombinant DNA molecules, pharmaceutical compositions containing hypoxia inducible factor alpha muteins and methods of using those compositions to treat hypoxia and ischemic related tissue damage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.