Covalently closed nucleic acid molecules for immunostimulation

US6849725B2 · kind B2 · utility

Assignee

• Mologen Forschungs Entwicklungs und Vertriebs GmbH · DE

Inventors

• Claas Junghans · Berlin, DE
• Burghardt Wittig · Berlin, DE
• Sven König Merediz · Berlin, DE
• Matthias Schroff · Berlin, DE

Key dates

• Filing date: Jan 24, 2002
• Grant date: Feb 1, 2005
• Expiry date: Aug 9, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/53
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Short deoxyribonucleic acid molecules that are partially single-stranded, dumbbell-shaped, and covalently closed, which contain one or more unmethylated cytosine guanosine motif (CpG motif) and exhibit immunomodifying effects. Such molecules can be used for immunostimulation applications in humans or vertebrates.