Patent · US Expired

Liquid analysis cartridge

US6852284B1 · kind B1 · utility

132Cited by
111References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 13, 2000
Grant dateFeb 8, 2005
Priority date
Expiry dateJun 22, 2021

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/2575
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of article capture regions. The storage channel is preferably an isotropic spatially periodic channel. Sedimented particles can be resuspended following storage. This invention further provides a microfluidic analysis cartridge having a convoluted storage channel therein. The sample analysis can use optical, electrical, pressure sensitive, or flow sensitive detection. A plurality of analysis channels can be included in a single cartridge. The analysis channels can be joined to reagent inlets for diluents, indicators or lysing agents. A mixing channel can be positioned between the reagent inlet and the analysis region to allow mixing and reaction of the reagent. The cartridge can include additional valves and pumps for flow management. The analysis cartridge can be a self-contained disposable cartridge having an integral waste storage container. This invention further provides a sheath flow assembly. The sheath flow assembly includes a sample channel and first and second sheath fluid channels positi…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.