Carvedilol-galenics

US6852337B2 · kind B2 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Rolf-Dieter Gabel · Schwetzingen, DE
• Walter Preis · Neustadt, DE
• Alexander Wirl · Heuchelheim, DE

Key dates

• Filing date: Oct 22, 2002
• Grant date: Feb 8, 2005
• Expiry date: Oct 22, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/454
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the preparation of fast-dissolving pharmaceutical preparations from difficultly soluble active substances, wherein an aqueous suspension is made from the active substance and one or more water-soluble adjuvants and then the resulting aqueous suspension is processed, with removal of the water, by methods conventional per se, to form solid pharmaceutical preparations. The invention also relates to fast-dissolving pharmaceutical preparations of active substances having a dissolution rate of at least 70% after 30 minutes, prepared in accordance with the process of the invention.