Transgenic circulating endothelial cells
US6852537B2 · kind B2 · utility
9Cited by
7References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2001 |
| Grant date | Feb 8, 2005 |
| Priority date | — |
| Expiry date | Nov 29, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process is provided for expanding the population of endothelial cells obtained from peripheral blood which can be transformed with a vector comprising a DNA sequence encoding a preselected bioactive polypeptide. The resulting transgenic endothelial cells are useful to biocompatibilize implantable medical devices or can be used directly, as for gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.