Method of identifying toxic agents using NSAID-induced differential gene expression in liver
US6852845B1 · kind B1 · utility
3Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2000 |
| Grant date | Feb 8, 2005 |
| Priority date | — |
| Expiry date | Aug 27, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods of identifying toxic agents, e.g., hepatotoxic agents, using differential gene expression. Also provided are methods of predicting the risk level and or injury type of NSAIDs. Also disclosed are novel nucleic acid sequences whose expression is differentially regulated by NSAIDs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.