Thioketals and thioethers for inhibiting the expression of VCAM-1
US6852878B2 · kind B2 · utility
12Cited by
21References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 21, 2001 |
| Grant date | Feb 8, 2005 |
| Priority date | — |
| Expiry date | Sep 2, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/67
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.