Administration of anti-inflammatory drugs into the central nervous system
US6853858B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 14, 2002 |
| Grant date | Feb 8, 2005 |
| Priority date | — |
| Expiry date | May 23, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/36082
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Apparatus is provided for delivering a Non Steroidal Anti-Inflammatory Drug (NSAID) supplied to a body of a subject for delivery to at least a portion of a central nervous system (CNS) of the subject via a systemic blood circulation of the subject, including a stimulator adapted to stimulate at least one site of the subject, so as to cause an increase in passage of the NSAID from the systemic blood circulation across a blood brain barrier (BBB) of the subject to the portion of the CNS, during at least a portion of the time that the NSAID is present in the blood, the site selected from the list consisting of: a sphenopalatine ganglion (SPG) of the subject, an anterior ethmoidal nerve of the subject, a posterior ethmoidal nerve of the subject, a communicating branch between an anterior ethmoidal nerve and a retro-orbital branch of an SPG of the subject, a communicating branch between a posterior ethmoidal nerve and a retro-orbital branch of an SPG of the subject, a greater palatine nerve of the subject, a lesser palatine nerve of the subject, a sphenopalatine nerve of the subject, a communicating branch between a maxillary nerve and an SPG of the subject, a nasopalatine nerve of the …
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.