Patent · US Expired

Cell volume-regulated human kinase h-sgk

US6855520B2 · kind B2 · utility

0Cited by

1References

15Claims

0Family size

Inventors

Florian Lang · Gilching, DE
Siegfried Waldegger · Marburg, DE

Key dates

Filing date	Dec 4, 2001
Grant date	Feb 15, 2005
Priority date	—
Expiry date	Oct 18, 2022

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the cloning and characterization of a human serine/threonine kinase (h-sgk: serum and glucocorticoid dependent kinase). The invention furthermore relates to reagents for diagnosing conditions associated with a change in cell volume and/or in “macromolecular crowding” in the body, such as, for example, hypernatremia, hyponatremia, diabetes mellitus, renal failure, hypercatabolism, hepatic encephalopathy, inflammation and microbial or viral infections. The present invention additionally relates to pharmaceuticals comprising the h-sgk, nucleic acids which code for the h-sgk, or receptors, in particular antibodies, which specifically bind to the h-sgk.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.