Stimulation of cartilage growth with agonists of the non-proteolytically activated thrombin receptor
US6855687B2 · kind B2 · utility
5Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2002 |
| Grant date | Feb 15, 2005 |
| Priority date | — |
| Expiry date | Jan 16, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method of stimulating cartilage growth, repair or regeneration at a site in a subject in need of such growth, repair or regeneration. The method comprises the step of administering a therapeutically effective amount of an agonist of the non-proteolytically activated thrombin receptor to the site.Also disclosed is a method of stimulating the proliferation and expansion of chrondrocytes in vitro. The method comprises culturing chrondrocytes in the presence of a stimulating amount of an NPAR agonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.