1-alkyl-2-aryl-benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives

US6855714B2 · kind B2 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Thorsten Blume · Schildow, DE
• Wolfgang Halfbrodt · Berlin, DE
• Joachim Kuhnke · Leverkusen, DE
• Ursula Moenning · Mölln, DE
• Herbert Schneider · Berlin, DE
• Bernd Elger · Neustadt, DE

Key dates

• Filing date: Jul 5, 2002
• Grant date: Feb 15, 2005
• Expiry date: Jul 5, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to novel benzimidazole derivatives with general formula I, whereby radicals R1, R2, R3, A, B and Y have the meanings that are indicated in the description and the claims, the use of these compounds for the production of a pharmaceutical agent for treating and for preventing diseases that are associated with microglia activation, as well as pharmaceutical preparations that contain these compounds.