Nitrogen-based camptothecin derivatives
US6855720B2 · kind B2 · utility
10Cited by
17References
29Claims
0Family size
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Key dates
| Filing date | Jun 14, 2002 |
| Grant date | Feb 15, 2005 |
| Priority date | — |
| Expiry date | Jun 14, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
(20S) esters of camptothecin analogs are provided. The compounds are (20S) esters of an aminoalkanoic acid or an imidoalkanoic acid and camptothecin, which is optionally substituted at the 7, 9, 10, 11, and 12 positions of the camptothecin ring. The compounds are useful for treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.