Powder processing with pressurized gaseous fluids

US6858166B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim Pharmaceuticals, Inc. · US

Inventors

• Said Saim · Lawrence, US
• Stephen Horhota · Brookfield, US
• Kenneth James Koenig · New Milford, US
• David Bochniak · Southbury, US

Key dates

• Filing date: Oct 10, 2002
• Grant date: Feb 22, 2005
• Expiry date: Jan 31, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1623
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed is a method of small particle precipitation, retention and dispersion of a solid or semi-solid material onto or into a carrier material. In this method, solute particles are precipitated from a pressurized gaseous fluid solution or a liquid solution and effectively retained and dispersed within a carrier material. This technique can be advantageously used in pharmaceutical processing to produce a blend of solid or semi-solid material particles and carrier material, a granulation of the solid or semi-solid material particles with carrier material, carrier material partially or fully coated with the solid or semi-solid material particles, or mixtures thereof.