Compositions and methods for the therapy and diagnosis of lung cancer

US6858204B2 · kind B2 · utility

Assignee

• Corxia Corporation · US

Inventors

• Robert A. Henderson · Seattle, US
• Tongtong Wang · Beijing, CN
• Yoshihiro Watanabe · Yokohama, JP
• Jeffrey C. Johnson · Flemington, US
• Marc Retter · Carnation, US
• Margarita Durham · Seattle, US
• Darrick Carter · Seattle, US
• Gary Fanger · Mill Creek, US
• Thomas S. Vedvick · Federal Way, US
• Chaitanya S. Bangur · Seattle, US
• Andria McNabb · Renton, US

Key dates

• Filing date: Oct 29, 2001
• Grant date: Feb 22, 2005
• Expiry date: Feb 2, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.