Mycobacterial sulfation pathway proteins and methods of use thereof
US6858213B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Apr 19, 2002 |
| Grant date | Feb 22, 2005 |
| Priority date | — |
| Expiry date | Apr 19, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel mycobacterial sulfation pathway enzymes and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting growth and/or virulence of a pathogenic mycobacterium, and methods of treating disease conditions associated with a pathogenic mycobacterium, particularly by administering an inhibitor of a mycobacterial sulfation pathway enzyme.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.