Direct multiplex characterization of genomic DNA
US6858412B2 · kind B2 · utility
470Cited by
33References
47Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 24, 2001 |
| Grant date | Feb 22, 2005 |
| Priority date | — |
| Expiry date | Oct 24, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/686
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.