Halogenated sulphamate-, phosphonate-, thiophosphonate-, sulphonate- and sulphonamide- compounds as inhibitors of steroid sulphatase
US6858597B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Jun 7, 2002 |
| Grant date | Feb 22, 2005 |
| Priority date | — |
| Expiry date | Jun 7, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound is described. The compound has the formula (Ia) as presented in the FIG. 1; wherein: X is a ring having at least 4 atoms in the ring; K is hydrocarbyl group; Rh1 is an optional halo group; Rh2 is an optional halo group; at least one of Rh1 and Rh2 is present; Rs is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group. The compound is capable of inhibiting steroid sulphatase (STS) activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.