Patent · US Expired

Cyclohepta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives

US6858604B2 · kind B2 · utility

3Cited by
15References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 2, 2001
Grant dateFeb 22, 2005
Priority date—
Expiry dateJul 17, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/24
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention provides compounds of the formula: wherein R1 and R2 are each, independently, H, alkyl, cycloalkyl, —CH2-cycloalkyl, alkoxy, halogen, fluorinated alkyl, —CN, —NH—SO2-alkyl, —SO2—NH-alkyl, alkyl amide, amino, alkylamino, dialkylamino, fluorinated alkoxy, acyl, or phenoyl or thiophenoyl; R3 and R4 are each, independently, H, alkyl or cycloalkyl; R5 is H or alkyl; R6 is H or; and the dashed line indicates an optional double bond; or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions and methods utilizing these compounds for the treatment or prevention of disorders including obsessive-compulsive disorder, depression, anxiety, generalized anxiety disorder, schizophrenia, migraine, sleep disorders, eating disorders, obesity, epilepsy, and spinal cord injury.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.