Microcrystalline cellulose cushioning granules
US6858725B1 · kind B1 · utility
7Cited by
10References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2000 |
| Grant date | Feb 22, 2005 |
| Priority date | — |
| Expiry date | Jan 10, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2301/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Granulation of microcrystalline cellulose with a granulating fluid consisting of water and a water-miscible, volatile, polar organic solvent yields porous granules which are comprised of particles that are larger than the ungranulated microcrystalline cellulose. This granulated microcrystalline cellulose is capable of cushioning controlled release particles and barrier coated particles from the compression forces used in tableting, thereby maintaining the physical integrity of the components of the tablet.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.