Patent · US Expired

Use of fumaric acid derivatives for treating mitochondrial diseases

US6858750B2 · kind B2 · utility

49Cited by
24References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 11, 2000
Grant dateFeb 22, 2005
Priority date
Expiry dateDec 11, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the use of individual fumaric acid derivatives or mixtures thereof for preparing a pharmaceutical composition for treating mitochondrial diseases, especially for treating Parkinson's syndrome, Alzheimer's disease, Chorea Huntington disease, retinopathia pigmentosa and mitochondrial encephalomyopathy. Preferably, the fumaric acid derivative(s) is/are those selected from the group consisting of fumaric acid dialkyl esters or fumaric acid monoalkyl esters in the form of the free acid or a salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.