Method of particle formation
US6860907B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 7, 2000 |
| Grant date | Mar 1, 2005 |
| Priority date | — |
| Expiry date | Jan 28, 2021 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D11/0488
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention provides a method for forming particles of a target substance, comprising (a) co-introducing into a particle formation vessel, under controlled temperature and pressure, a supercritical or near-critical anti-solvent fluid; a “target solution or suspension” of the target in a first vehicle; and a second vehicle which is soluble in the anti-solvent fluid; and (b) using the anti-solvent to disperse the target solution/suspension and the second vehicle, and to extract the vehicles, substantially simultaneously and substantially immediately on introduction of the fluids into the particle formation vessel, wherein the second vehicle is immiscible with the first, and wherein contact between the target solution/suspension and the second vehicle occurs a sufficiently short period of time before their dispersion by the anti-solvent, and with sufficient physical mixing, as to allow only insignificant, if any, phase separation to occur between the two vehicles between their contact with one another and their dispersion
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.