Compounds and methods for the modulation of CD154
US6861504B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 30, 2001 |
| Grant date | Mar 1, 2005 |
| Priority date | — |
| Expiry date | Jun 11, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that are capable of modulating CD154 mobilization and that are useful for stabilizing the thrombotic process and reducing the activation of cells involved in an inflammatory response. The present invention also relates to methods useful for identifying such compounds. The present invention also relates to the treatment of platelets for transfusion with metalloproteinase inhibitors to treat or prevent inflammation. The present invention also includes compositions and methods to treat injury and disease related to such biological processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.