Enhanced sequencing by hybridization using pools of probes
US6864052B1 · kind B1 · utility
278Cited by
4References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 6, 2000 |
| Grant date | Mar 8, 2005 |
| Priority date | — |
| Expiry date | Jan 6, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6874
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.