Dipeptide inhibitors of β-secretase
US6864240B1 · kind B1 · utility
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37Claims
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Key dates
| Filing date | Jun 15, 2000 |
| Grant date | Mar 8, 2005 |
| Priority date | — |
| Expiry date | Jan 2, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0205
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Dipeptide derived inhibitors of the β-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Aβ peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Aβ peptide formation and in pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.