Anhydrous crystalline 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine hemisulfate as useful as an antiviral agent
US6864244B2 · kind B2 · utility
15Cited by
1References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2003 |
| Grant date | Mar 8, 2005 |
| Priority date | — |
| Expiry date | Dec 9, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the hemisulfate salt of 1-[4(S)-azido-2(S),3(R)-dihydroxy-4-(hydroxymethyl)-1(R)-cyclopentyl]cytosine (Ia) with improved stability and physical properties which facilitate manufacturing, handling and formulating I and polymorphic crystalline forms thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.