Bi-laminar, hyaluronan coatings with silver-based anti-microbial properties
US6866859B2 · kind B2 · utility
30Cited by
45References
20Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 29, 2001 |
| Grant date | Mar 15, 2005 |
| Priority date | — |
| Expiry date | Jul 28, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/0056
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An article including a surface having a coating thereon, in which the coating includes a base coat, firmly adhered to the surface, and a hydrophilic, biocompatible top-coat. An antibiotic ceramic component is dispersed in one or both of the base coat and top-coat. Preferably, the ceramic component is dispersed in the base coat. In a preferred embodiment, the ceramic component is a zeolite with silver ions exchanged onto internal acidic sites of the zeolite, and the top-coat includes a polysaccharide, such as hyaluronan. The zeolite is highly effective in imparting anti-microbial character to the coating.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.