Method and apparatus for increasing the dynamic range and accuracy of binding assays
US6867005B2 · kind B2 · utility
5Cited by
45References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 24, 2001 |
| Grant date | Mar 15, 2005 |
| Priority date | — |
| Expiry date | Feb 5, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/6428
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to methods for increasing the dynamic range and accuracy of assays in which the presence, absence, activity or concentration of a target analyte is assayed by the emission or quenching of a light signal, or by a change (i.e., an evolution or loss) of a light signal in two or more time intervals. In preferred embodiments multiple digitized images are captured at varying times, and the images analyzed to identify captured images within the dynamic range of the assay. The invention further relates to apparati capable of implementing such methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.