Inhibition of angiogenesis by high molecular weight kininogen domain 3 peptide analogs
US6869931B1 · kind B1 · utility
5Cited by
7References
16Claims
0Family size
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Key dates
| Filing date | Dec 15, 1999 |
| Grant date | Mar 22, 2005 |
| Priority date | — |
| Expiry date | Dec 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peptide analogs the high molecular weight kininogen domain 3 are potent inhibitors of angiogenesis. The peptides have the formula (a) X1-Asn-Asn-Ala-Thr-Phe-Tyr-Phe-Lys-X2, (b) X3-Cys-Val-Gly-Cys-X4, (c) X5-Leu-Asp-X7-Asn-Ala-Glu-Val-Tyr-X6, or (d) Tyr-Phe-Ile-Asp-Phe-Val-Ala-Arg-Glu-Thr-Thr-X7-Ser-Lys-Glu-Ser
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.