Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
US6869956B2 · kind B2 · utility
6Cited by
14References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 1, 2002 |
| Grant date | Mar 22, 2005 |
| Priority date | — |
| Expiry date | Feb 1, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes methods of preventing and treating inflammatory and immune-related diseases or disorders using inhibitors of IκB kinase (IKK). Also described are IKK inhibitors effective for the prevention and treatment of inflammatory and immune-related diseases or disorders, as demonstrated in vivo. Further embodiments of the present invention relate to a specific IKK inhibitors, 4(2′-aminoethyl)amino-1,8-dimethylimidazo(1,2-a) quinoxaline and compounds of formula (I), salts thereof, and pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.