Highly productive packaging lines
US6872528B2 · kind B2 · utility
16Cited by
4References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 2001 |
| Grant date | Mar 29, 2005 |
| Priority date | — |
| Expiry date | Jul 14, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a packaging eukaryotic cell for the production of defective infections viruses carrying a transgene, characterized in that it is deficient in one cell function essential to its growth, in particular in the presence of a selection culture medium, the function being capable of being restored by the expression of an exogenous sequence introduced in the cell: either with a vector carrying transcomplementing functions of packaging cells; or with a vector carrying a transgene, and enabling the selection in a selective medium of cells carrying the said exogenous sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.