Patent · US Expired

Polymorphic forms of sertraline hydrochloride

US6872853B1 · kind B1 · utility

11Cited by
9References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 23, 2000
Grant dateMar 29, 2005
Priority date
Expiry dateFeb 10, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A cystalline form of sertraline hydrochloride was found, referred to hereinafter as polymorphic form CSC2 having a dissolution rate which surprisingly will increase rate of absorption of a drug. Furthermore, different crystalline forms of sertraline hydrochloride alcohol solvates, crystalline forms of sertraline hydrochloride hydrates, referred to hereinafter as polymorphic form CSC1, a process for the preparation of the amorphous form of sertraline hydrochloride, and different processes for the preparation of polymorphic forms I, II, V, and T1 are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.