DNA polymerases having amino acid substitutions and homologs thereof
US6875573B2 · kind B2 · utility
7Cited by
3References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 2002 |
| Grant date | Apr 5, 2005 |
| Priority date | — |
| Expiry date | Jul 8, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/1252
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Thermostable DNA polymerases both in native form and having single amino acid substitutions and optionally N-terminal deletions are disclosed. These polymerases exhibit a substantial improvement of DNA sequencing performance compared to Taq DNA polymerase. The instant DNA polymerases also possess improved salt tolerance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.