3′-prodrugs of 2′-deoxy-β-L-nucleosides
US6875751B2 · kind B2 · utility
45Cited by
30References
25Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 15, 2001 |
| Grant date | Apr 5, 2005 |
| Priority date | — |
| Expiry date | Dec 19, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compound and compositions of 3′-esters of 2′-deoxy-β-L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compound and compositions of 3′,5′-diesters of 2′-deoxy-β-L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents, are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.