Patent · US Expired

Reagent for labelling nucleic acids

US6875850B2 · kind B2 · utility

4Cited by

3References

7Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Dieter Heindl · Munich, DE
Gregor Sagner · Penzberg, DE
Heribert Maerz · Wörth an der Donau, DE
Herbert von der Eltz · Spaichingen, DE

Key dates

Filing date	Aug 30, 2001
Grant date	Apr 5, 2005
Priority date	—
Expiry date	Jan 19, 2023

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2996
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention concerns a labelling reagent in which the label is bound via an amide bond and a linker to a residue of the molecule which is essentially characterized in that the N atom of the amide bond and the label are linked together directly by a covalent bond. In particular these are phosphoramidites or reactive supports suitable for nucleic acid synthesis. The invention also concerns processes for the production of such supports from suitable precursors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.