Patent · US Expired

Prolyl tripeptidyl peptidases nucleic acid of Porphyromonas gingivalis

US6875851B1 · kind B1 · utility

16Cited by
14References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 3, 2000
Grant dateApr 5, 2005
Priority date
Expiry dateMar 3, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K39/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides isolated polypeptides, prolyl tripeptidyl-peptidases, and active analogs, active fragments or active modifications thereof, having amidolytic activity for cleavage of a peptide bond present in a target peptide having at least 30 amino acids. Isolated nucleic acid fragments encoding isolated prolyl tripeptidyl-peptidases are also provided, as are methods of reducing growth of a bacterium by inhibiting a prolyl tripeptidyl-peptidase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.